Sleep in older adults, a MIRAGE?
- rajaduttamd
- Jul 1, 2025
- 1 min read
Summary: The MIRAGE Study on Mirtazapine for Chronic Insomnia in Older Adults
🔬 Study Type: Randomized, Double-Blind, Placebo-Controlled Trial
👵 Patient Population: Adults aged 65+ with chronic insomnia
💊 Intervention: Mirtazapine vs. Placebo (28 days)
📈 Primary Outcome: Mean change in Insomnia Severity Index (ISI) score
✅ Key Finding: Mirtazapine was superior to placebo in reducing insomnia symptoms.
⚠️ Important Consideration: Mild but clinically relevant adverse events were noted.
💡 Implication: Valuable insights for geriatric sleep management, emphasizing balanced decision-making on efficacy vs. side effects.




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