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Sleep in older adults, a MIRAGE?

  • rajaduttamd
  • Jul 1, 2025
  • 1 min read

Summary: The MIRAGE Study on Mirtazapine for Chronic Insomnia in Older Adults

  • 🔬 Study Type: Randomized, Double-Blind, Placebo-Controlled Trial

  • 👵 Patient Population: Adults aged 65+ with chronic insomnia

  • 💊 Intervention: Mirtazapine vs. Placebo (28 days)

  • 📈 Primary Outcome: Mean change in Insomnia Severity Index (ISI) score

  • Key Finding: Mirtazapine was superior to placebo in reducing insomnia symptoms.

  • ⚠️ Important Consideration: Mild but clinically relevant adverse events were noted.

    💡 Implication: Valuable insights for geriatric sleep management, emphasizing balanced decision-making on efficacy vs. side effects.



 
 
 

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