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Managing Alcohol Withdrawal in General Hospitals
The COVID-19 pandemic triggered an unprecedented surge in alcohol consumption, leading to a significant rise in hospitalizations for alcohol withdrawal syndrome (AWS) . For patients admitted to general hospitals, the sudden interruption of alcohol intake creates an iatrogenic risk for withdrawal, which can range from mild anxiety and tremors to life-threatening conditions like seizures and delirium tremens . Effective management begins with universal screening using validate
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Cholinergic Rebound in Clozapine Withdrawal
While withdrawal symptoms from typical antipsychotics are generally mild and self-limiting, clozapine discontinuation can trigger a severe clinical picture characterized by rapid-onset agitation, delirium, and psychosis. Research into three specific case reports highlights that these symptoms often manifest within days of stopping the medication. Patients may experience a clouding of consciousness, disorientation, and even physical complications like profuse diaphoresis, inco
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Quetiapine vs. Haloperidol: A New Look at Managing ICU Delirium
Delirium remains a significant challenge in intensive care units, affecting nearly 32% of all critically ill patients and surging as high as 91% for those on mechanical ventilation. While haloperidol has traditionally served as the first-line treatment, its association with distressing extrapyramidal side effects and severe sedation has led researchers to explore safer alternatives. A recent randomized controlled trial published in Neurocritical Care investigated whether que
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Psychological consequences of female genital mutilation: A mixed-method systematic review
This mixed-method systematic review by Reman et al. (2023) investigates the significant mental health burden associated with female genital mutilation/cutting (FGM/C). By analyzing 14 studies published between 2010 and 2020, the researchers found that women who have undergone FGM/C experience a significantly higher prevalence of psychological disorders compared to those who have not. The primary clinical diagnoses identified include post-traumatic stress disorder (PTSD), depr
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