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Microdose or Mirage? What the Randomized Evidence Actually Shows
A small dose with an enormous reputation Microdosing usually means taking a sub-hallucinogenic amount of a psychedelic such as LSD or psilocybin on intermittent days. Its modern appeal is easy to understand. The dose is presented as small enough to preserve ordinary functioning, yet potentially large enough to improve mood, creativity, focus, or emotional flexibility. The stories are compelling. They are also difficult to interpret. Someone who begins microdosing may simultan
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Maternal Suicide and the Postpartum Gap
The 2026 MBRRACE-UK report, Saving Lives, Improving Mothers’ Care, offers a disturbing reminder that the danger associated with pregnancy does not end at delivery—or at the traditional six-week postpartum visit. In the United Kingdom, suicide remained the leading cause of maternal death between six weeks and one year after the end of pregnancy. Psychiatric illness also figured prominently during pregnancy and the early postpartum period. Among women who died from direct or in
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The Youth Mental-Health Story May Be Changing Shape
A global meta-analysis of 418,528 young people found no consistent rise in overall emotional and behavioral symptom burden through 2019. Beneath that apparently stable total, however, the pattern of distress was changing. The sentence every generation repeats “Kids these days” is rarely a neutral observation. It usually carries a diagnosis: children are less resilient, less disciplined, more anxious or simply worse off than those who came before them. The concern is not frivo
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When Relapse Comes Fast: Withdrawal, Illness—or Something More Complicated?
Rapid relapse after an antipsychotic is stopped is sometimes interpreted as evidence of pharmacological withdrawal. A new individual-participant-data meta-analysis in The Lancet Psychiatry tested whether that explanation fits the observed clinical pattern. The answer is nuanced. Rapid and delayed relapse trajectories were identified, but rapid relapse was not significantly concentrated among people randomized to discontinue paliperidone. This weighs against a common, distinct
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