Understanding "Spice"-Induced Psychosis: A New Clinical Frontier Synthetic cannabinoid receptor agonists (SCRAs), often sold under street names like "Spice" or "K2," have become a global public health concern due to their potent and often unpredictable psychiatric effects. Unlike natural cannabis, these laboratory-engineered molecules bind to brain receptors with much higher affinity, frequently triggering acute psychotic episodes characterized by severe agitation, aggression

Methamphetamine use has emerged as a global public health crisis, second only to cannabis in its prevalence of abuse. While the drug is well-known for its stimulant properties on the central nervous system, its devastating impact on the heart—specifically methamphetamine-associated cardiomyopathy (MAC)—is increasingly reported yet remains under-studied. Clinically, MAC often presents as dilated cardiomyopathy, characterized by enlarged cardiac chambers and a severely reduced

The COVID-19 pandemic triggered an unprecedented surge in alcohol consumption, leading to a significant rise in hospitalizations for alcohol withdrawal syndrome (AWS) . For patients admitted to general hospitals, the sudden interruption of alcohol intake creates an iatrogenic risk for withdrawal, which can range from mild anxiety and tremors to life-threatening conditions like seizures  and delirium tremens . Effective management begins with universal screening using validate

While withdrawal symptoms from typical antipsychotics are generally mild and self-limiting, clozapine discontinuation can trigger a severe clinical picture characterized by rapid-onset agitation, delirium, and psychosis. Research into three specific case reports highlights that these symptoms often manifest within days of stopping the medication. Patients may experience a clouding of consciousness, disorientation, and even physical complications like profuse diaphoresis, inco