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Quetiapine vs. Haloperidol: A New Look at Managing ICU Delirium
Delirium remains a significant challenge in intensive care units, affecting nearly 32% of all critically ill patients and surging as high as 91% for those on mechanical ventilation. While haloperidol has traditionally served as the first-line treatment, its association with distressing extrapyramidal side effects and severe sedation has led researchers to explore safer alternatives. A recent randomized controlled trial published in Neurocritical Care investigated whether que
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Psychological consequences of female genital mutilation: A mixed-method systematic review
This mixed-method systematic review by Reman et al. (2023) investigates the significant mental health burden associated with female genital mutilation/cutting (FGM/C). By analyzing 14 studies published between 2010 and 2020, the researchers found that women who have undergone FGM/C experience a significantly higher prevalence of psychological disorders compared to those who have not. The primary clinical diagnoses identified include post-traumatic stress disorder (PTSD), depr
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Treatment outcomes in functional neurological disorder: a systematic review and meta-analysis exploring the influence of symptom chronicity
Conversion disorder—now termed Functional Neurological Disorder (FND) —has long been viewed through a pessimistic lens, particularly when symptoms persist over time. A major 2025 systematic review and meta-analysis in BMJ Neurology Open challenges that assumption by examining whether symptom chronicity actually limits treatment response . Drawing on 63 studies (27 included in meta-analyses, 885 patients), the authors evaluated outcomes across functional motor disorders,...
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Reducing Mortality with ECT: New Insights from a Global Meta-Analysis
Electroconvulsive therapy (ECT) has long been recognized as a powerful tool for treatment-resistant mood disorders, but its impact on long-term survival has remained a subject of clinical debate. A comprehensive new systematic review and meta-analysis published in BMJ Mental Health provides clear evidence that ECT is associated with a 30% reduction in the risk of all-cause mortality among patients with severe unipolar or bipolar depression. This protective effect was found
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