A meta-analysis of 96,676 people linked short-form video use with several forms of psychological distress. Its most important finding was not that every minute is harmful, but that compulsive use appears more closely tied to poor mental health than routine use. A feed with no natural stopping point Short-form video has changed how millions of people encounter entertainment, news, education, health advice, and one another. Each clip is brief; the session often is not. The form

When a Weight-Loss Medicine Meets Alcohol Use Disorder A new randomized trial of oral semaglutide found fewer heavy-drinking days and fewer alcohol-related consequences—but missed its primary craving outcome. The mixed result is precisely why the study deserves attention without hype. An unexpected therapeutic bridge GLP-1 receptor agonists entered public consciousness as treatments for diabetes and obesity. Yet clinicians and patients began reporting something more difficult

What is the “right” plasma clozapine concentration? A new dose-response meta-analysis in Psychiatry Research offers several provocative numbers. But its most important contribution may be its warning against treating those numbers as universal thresholds. Fornaro and colleagues examined the relationships between plasma clozapine and norclozapine concentrations, therapeutic response and adverse outcomes in people with schizophrenia-spectrum disorders. Their findings reinforce

When should an antipsychotic be judged effective—or ineffective? The usual answer is expressed in weeks. But a new study in The Lancet Psychiatry suggests that the more clinically useful question may be: Which symptoms are we waiting to improve? Leucht and colleagues analyzed individual-participant data from six antipsychotic trials involving 2,079 people with acute schizophrenia. Their findings show that the major symptom domains of schizophrenia improve on meaningfully diff